Fexagratinib; AZD4547

Fexagratinib; AZD4547
  • Name: Fexagratinib; AZD4547
  • Catalog No.: CPDB0053
  • CAS No.: 1035270-39-3
  • Molecular Weight: 463.6
  • Chemical Formula: C26H33N5O3
  • For scientific research only, not for patients.

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    1g In Stock 750
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    Chemical Name:

    N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

    SMILES Code: 

    O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4)C=C3

    InChi Code:

    InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+

    InChi Key:

    VRQMAABPASPXMW-HDICACEKSA-N

    Keyword:

    1035270-39-3;CAS:1035270-39-3;CAS:1035270-39-3;AZD4547;AZD-4547;AZD 4547;Fexagratinib

    Solubility: Soluble in DMSO

    Storage: Refrigerator

    Description: 

    AZD 4547 is a selective inhibitor of the fibroblast growth factor receptor (FGFR) tyrosine kinase with IC50 values of 0.2, 2.5, and 1.8 nM for FGFR1, 2, and 3, respectively.

    Target: FGFR




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