Fexagratinib; AZD4547

Chemical Name:

N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

SMILES Code: 

O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4)C=C3

InChi Code:

InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+

InChi Key:

VRQMAABPASPXMW-HDICACEKSA-N

Keyword:

1035270-39-3；CAS：1035270-39-3；CAS:1035270-39-3；AZD4547；AZD-4547；AZD 4547；Fexagratinib

Solubility: Soluble in DMSO

Storage: Refrigerator

Description: 

AZD 4547 is a selective inhibitor of the fibroblast growth factor receptor (FGFR) tyrosine kinase with IC50 values of 0.2, 2.5, and 1.8 nM for FGFR1, 2, and 3, respectively.

Target: FGFR