RGX-104 HCl

RGX-104 HCl
  • Name: RGX-104 HCl
  • Catalog No.: CPDB1632
  • CAS No.: 610318-03-1
  • Molecular Weight: 632.5452
  • Chemical Formula: C34H34Cl2F3NO3
  • For scientific research only, not for patients.

    Product Detail

    Product Tags

    Pack Size Availability Price (USD)
    100mg In Stock 500
    500mg In Stock 800
    1g In Stock 1200
    More Sizes Get Quotes Get Quotes

    Chemical Name:

    (R)-2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]-3-methylpropoxy]phenyl]acetic acid hydrochloride

    SMILES Code: 


    InChi Code:


    InChi Key:



    RGX-104 HCl, RGX-104, RGX104, RGX 104, 610318-03-1

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).


    RGX-104 is a liver X receptor beta agonist with potential immunomodulating and antineoplastic activities. Upon oral administration, RGX-104 selectively targets and binds to LXRbeta, thereby activating LXRbeta-mediated signaling, leading to the transcription of certain tumor suppressor genes and the downregulation of certain tumor promoter genes. This particularly activates the expression of apolipoprotein E (ApoE), a tumor suppressor protein, in tumor cells and certain immune cells. This activates the innate immune system, resulting in depletion of immunosuppressive myeloid-derived suppressor cells (MDSCs), tumor cells and endothelial cells in the tumor microenvironment. This reverses immune evasion, enhances anti-tumor immune responses and inhibits proliferation of tumor cells.

    Target: LXRbeta

  • Previous:
  • Next:

  • Related Products

    WhatsApp Online Chat !