Alrizomadlin; AA115; APG 115

Chemical Name:

4-((3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic acid

SMILES Code: 

O=C1NC2=CC(Cl)=CC=C2[C@]13C4(CCCCC4)N(CC)[C@@H](C(NC5(CC6)CCC6(C(O)=O)CC5)=O)[C@@H]3C7=C(F)C(Cl)=CC=C7

InChi Code:

InChI=1S/C34H38Cl2FN3O4/c1-2-40-27(28(41)39-32-16-13-31(14-17-32,15-18-32)30(43)44)25(21-7-6-8-23(36)26(21)37)34(33(40)11-4-3-5-12-33)22-10-9-20(35)19-24(22)38-29(34)42/h6-10,19,25,27H,2-5,11-18H2,1H3,(H,38,42)(H,39,41)(H,43,44)/t25-,27+,31?,32?,34+/m0/s1

InChi Key:

YJCZPJQGFSSFOL-MNZPCBJKSA-N

Keyword:

1818393-16-6；CAS：1818393-16-6；CAS:1818393-16-6；AA-115; AA 115; AA115; APG 115; APG115; APG-115; Alrizomadlin

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Alrizomadlin (APG-115) is an orally active small molecule MDM2 protein inhibitor that can bind to MDM2 protein.

Target: MDM2