PHA-408

For scientific research only, not for patients.
Product Detail
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Chemical Name:
8-(5-Chloro-2-(4-methylpiperazin-1-yl)isonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide
SMILES Code:
O=C(C1=NN(C2=CC=C(F)C=C2)C3=C1CCC4=CC=C(NC(C5=C(Cl)C=NC(N6CCN(C)CC6)=C5)=O)C=C43)N
InChi Code:
InChI=1S/C29H27ClFN7O2/c1-36-10-12-37(13-11-36)25-15-23(24(30)16-33-25)29(40)34-19-6-2-17-3-9-21-26(28(32)39)35-38(27(21)22(17)14-19)20-7-4-18(31)5-8-20/h2,4-8,14-16H,3,9-13H2,1H3,(H2,32,39)(H,34,40)
InChi Key:
ZLEZHGHFWIHCGU-UHFFFAOYSA-N
Keyword:
503555-55-3;CAS:503555-55-3;CAS:503555-55-3;PHA 408;PHA408;PHA-408
Solubility: Soluble in DMSO
Storage: -20°C
Description:
PHA 408 (PHA-408) is an effective, selective, and orally active inhibitor of I κ B kinase-2 (IKK-2).
Target: IκB kinase-2 (IKK-2)

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