PHA-408

Chemical Name:

8-(5-Chloro-2-(4-methylpiperazin-1-yl)isonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

SMILES Code: 

O=C(C1=NN(C2=CC=C(F)C=C2)C3=C1CCC4=CC=C(NC(C5=C(Cl)C=NC(N6CCN(C)CC6)=C5)=O)C=C43)N

InChi Code:

InChI=1S/C29H27ClFN7O2/c1-36-10-12-37(13-11-36)25-15-23(24(30)16-33-25)29(40)34-19-6-2-17-3-9-21-26(28(32)39)35-38(27(21)22(17)14-19)20-7-4-18(31)5-8-20/h2,4-8,14-16H,3,9-13H2,1H3,(H2,32,39)(H,34,40)

InChi Key:

ZLEZHGHFWIHCGU-UHFFFAOYSA-N

Keyword:

503555-55-3；CAS：503555-55-3；CAS:503555-55-3；PHA 408；PHA408；PHA-408

Solubility: Soluble in DMSO

Storage: -20°C

Description: 

PHA 408 (PHA-408) is an effective, selective, and orally active inhibitor of I κ B kinase-2 (IKK-2).

Target: IκB kinase-2 (IKK-2)