ART812

Chemical Name:

(2S,3S,4S)-N-(3-Chloro-4-fluorophenyl)-3,4-dihydroxy-N-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-5-oxopyrrolidine-2-carboxamide

SMILES Code: 

O=C([C@H]([C@H](O)[C@@H]1O)N(C2=NC(C)=CC(C(F)(F)F)=C2)C1=O)N(C3=CC=C(F)C(Cl)=C3)C

InChi Code:

InChI=1S/C19H16ClF4N3O4/c1-8-5-9(19(22,23)24)6-13(25-8)27-14(15(28)16(29)18(27)31)17(30)26(2)10-3-4-12(21)11(20)7-10/h3-7,14-16,28-29H,1-2H3/t14-,15-,16-/m0/s1

InChi Key:

YJJOABOMFPGRED-JYJNAYRXSA-N

Keyword:

2607138-82-7；CAS：2607138-82-7；CAS:2607138-82-7；ART812；ART-812；ART 812

Solubility: 

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

ART812 is an orally effective inhibitor of DNA polymerase Pol θ.

Target: Polθ