LGH-447; PIM-447

Chemical Name:

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide

SMILES Code: 

O=C(NC1=C([C@H]2C[C@@H](N)C[C@@H](C)C2)C=CN=C1)C3=NC(C4=C(F)C=CC=C4F)=C(F)C=C3

InChi Code:

InChI=1S/C24H23F3N4O/c1-13-9-14(11-15(28)10-13)16-7-8-29-12-21(16)31-24(32)20-6-5-19(27)23(30-20)22-17(25)3-2-4-18(22)26/h2-8,12-15H,9-11,28H2,1H3,(H,31,32)/t13-,14+,15-/m0/s1

InChi Key:

VRQXRVAKPDCRCI-ZNMIVQPWSA-N

Keyword:

1210608-43-7；CAS：1210608-43-7；CAS:1210608-43-7；LGH-447; LGH 447; LGH447; PIM447; PIM-447; PIM 447; LGH447 free base

Solubility: Soluble in DMSO, not in water

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

PIM447 (LGH447) is an effective, oral, and selective pan PIM kinase inhibitor.

Target: PIM