BMS-986449

Chemical Name:

(S)-3-((R)-5-(6-amino-4,5-dimethylpyridin-2-yl)-4-fluoro-3-methyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione

SMILES Code: 

O=C1NC([C@@H](N2[C@H](C)C3=C(F)C(C4=CC(C)=C(C)C(N)=N4)=CC=C3C2=O)CC1)=O

InChi Code:

InChI=1S/C21H21FN4O3/c1-9-8-14(24-19(23)10(9)2)12-4-5-13-17(18(12)22)11(3)26(21(13)29)15-6-7-16(27)25-20(15)28/h4-5,8,11,15H,6-7H2,1-3H3,(H2,23,24)(H,25,27,28)/t11-,15+/m1/s1

InChi Key:

CNRNDVOTRSDMEF-ABAIWWIYSA-N

Keyword:

BMS-986449; BMS986449; BMS 986449

Solubility: 

Storage: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Description: 

BMS-986449 is a CELMoD molecular glue and a degradation agent for IKZF2/IKZF4.

Target: IKZF2/IKZF4