BI-4142

Chemical Name:

1-(4-(8-((3-Methyl-4-((1-methyl-1H-benzo[d]imidazol-5-yl)oxy)phenyl)amino)pyrimido[5,4-d]pyrimidin-2-yl)piperazin-1-yl)prop-2-en-1-one

SMILES Code: 

C=CC(N1CCN(C2=NC=C(N=CN=C3NC4=CC=C(OC5=CC=C6N(C)C=NC6=C5)C(C)=C4)C3=N2)CC1)=O

InChi Code:

InChI=1S/C28H27N9O2/c1-4-25(38)36-9-11-37(12-10-36)28-29-15-22-26(34-28)27(31-16-30-22)33-19-5-8-24(18(2)13-19)39-20-6-7-23-21(14-20)32-17-35(23)3/h4-8,13-17H,1,9-12H2,2-3H3,(H,30,31,33)

InChi Key:

JKBYBPNRTMHEGS-UHFFFAOYSA-N

Keyword:

2682003-36-5；CAS：2682003-36-5；CAS:2682003-36-5；BI4142; BI-4142; BI 4142

Solubility: 

Storage: 

Description: 

BI-4142 is an effective, highly selective, and orally active HER2 inhibitor.

Target: HER2