Glecirasib; JAB-21822

Glecirasib; JAB-21822
  • Name: Glecirasib; JAB-21822
  • Catalog No.: CPDP801328
  • CAS No.: 2657613-87-9
  • Molecular Weight: 640.03
  • Chemical Formula: C31 H26 Cl F4 N7 O2
  • For scientific research only, not for patients.

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    Chemical Name:

    4-(4-acryloylpiperazin-1-yl)-7-(2-amino-3,4,5,6-tetrafluorophenyl)-6-chloro-1-(2-isopropyl-4-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carbonitrile

    SMILES Code: 

    FC1=C(F)C(C2=C(Cl)C=C(C(N3CCN(C(C=C)=O)CC3)=C(C#N)C(N4C5=C(C)C=CN=C5C(C)C)=O)C4=N2)=C(N)C(F)=C1F

    InChi Code:

    InChI=1S/C31H26ClF4N7O2/c1-5-19(44)41-8-10-42(11-9-41)29-16-12-18(32)27(20-21(33)22(34)23(35)24(36)25(20)38)40-30(16)43(31(45)17(29)13-37)28-15(4)6-7-39-26(28)14(2)3/h5-7,12,14H,1,8-11,38H2,2-4H3

    InChi Key:

    QRRJEUIQLZNPIO-UHFFFAOYSA-N

    Keyword:

    2657613-87-9;CAS:2657613-87-9;CAS:2657613-87-9;Glecirasib;JAB21822;JAB 21822;JAB-21822

    Solubility: 

    Storage: 

    Description: 

    Glecirasib (Compound 1-2; JAB-21822) is an orally active and effective KRAS G12C inhibitor.

    Target: KRAS G12C




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