Vazegepant; BMS 742413; BHV 3500

Chemical Name:

(R)-N-(3-(7-methyl-1H-indazol-5-yl)-1-(4-(1-methylpiperidin-4-yl)piperazin-1-yl)-1-oxopropan-2-yl)-4-(2-oxo-1,2-dihydroquinolin-3-yl)piperidine-1-carboxamide

SMILES Code: 

CN1CCC(N2CCN(C([C@H](NC(N3CCC(C4=CC(C=CC=C5)=C5NC4=O)CC3)=O)CC6=CC(C=NN7)=C7C(C)=C6)=O)CC2)CC1

InChi Code:

InChI=1S/C36H46N8O3/c1-24-19-25(20-28-23-37-40-33(24)28)21-32(35(46)43-17-15-42(16-18-43)29-9-11-41(2)12-10-29)39-36(47)44-13-7-26(8-14-44)30-22-27-5-3-4-6-31(27)38-34(30)45/h3-6,19-20,22-23,26,29,32H,7-18,21H2,1-2H3,(H,37,40)(H,38,45)(H,39,47)/t32-/m1/s1

InChi Key:

JJVAPHYEOZSKJZ-JGCGQSQUSA-N

Keyword:

1337918-83-8；CAS：1337918-83-8；CAS:1337918-83-8；Zavegepant, Vazegepant; BMS 742413; BMS-742413; BMS742413; BHV-3500; BHV 3500; BHV3500

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Vazegepant (Zavegepant) is an orally effective calcitonin gene-related peptide (CGRP) receptor antagonist.

Target: CGRP