GSK4418959; IDE275

Chemical Name:

(1R,2R,6S)-2-((2-fluoro-4-(trifluoromethyl)phenyl)carbamoyl)-6-(4-((N,1,2-trimethyl-1H-benzo[d]imidazole)-5-sulfonamido)phenyl)cyclohexane-1-carboxylic acid

SMILES Code: 

FC1=C(NC([C@@H]2CCC[C@H](C3=CC=C(N(C)S(C4=CC(N=C(C)N5C)=C5C=C4)(=O)=O)C=C3)[C@H]2C(O)=O)=O)C=CC(C(F)(F)F)=C1

InChi Code:

InChI=1S/C31H30F4N4O5S/c1-17-36-26-16-21(12-14-27(26)38(17)2)45(43,44)39(3)20-10-7-18(8-11-20)22-5-4-6-23(28(22)30(41)42)29(40)37-25-13-9-19(15-24(25)32)31(33,34)35/h7-16,22-23,28H,4-6H2,1-3H3,(H,37,40)(H,41,42)/t22-,23-,28-/m1/s1

InChi Key:

CPNRNECAIBPHJF-MVOZIGHISA-N

Keyword:

3064599-36-3；CAS：3064599-36-3；CAS:3064599-36-3；GSK4418959; GSK-4418959; GSK 4418959; IDE-275; IDE 275; IDE275

Solubility: 

Storage: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Description: 

GSK4418959 (IDE275) is a non covalent, reversible, selective, and orally active WRN helicase inhibitor.

Target: WRN