UT-155

Chemical Name:

(S)-N-(4-cyano-3-(trifluoromethyl)phenyl)-3-(5-fluoro-1H-indol-1-yl)-2-hydroxy-2-methylpropanamide

SMILES Code: 

O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)[C@@](C)(O)CN2C=CC3=C2C=CC(F)=C3

InChi Code:

InChI=1S/C20H15F4N3O2/c1-19(29,11-27-7-6-12-8-14(21)3-5-17(12)27)18(28)26-15-4-2-13(10-25)16(9-15)20(22,23)24/h2-9,29H,11H2,1H3,(H,26,28)/t19-/m0/s1

InChi Key:

CFSAYQVTXBMPRF-IBGZPJMESA-N

Keyword:

2031161-35-8；CAS:2031161-35-8；CAS：2031161-35-8；(S)-UT 155; (S) UT-155; (S)-UT-155; UT155; UT 155; UT-155

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

UT-155 is a potent selective androgen receptor degrader (SARD), markedly reducing the activity of wild-type and splice variant isoforms of AR, binding the amino-terminal transcriptional activation domain AF-1 and the carboxy-terminal ligand binding domain.

Target: Selective and effective androgen receptor (AR) antagonists