NBI-921352

NBI-921352
  • Name: NBI-921352
  • Catalog No.: CPD109440
  • CAS No.: 2154406-04-7
  • Molecular Weight: 460.59
  • Chemical Formula: C22H25FN4O2S2
  • For scientific research only, not for patients.

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    Chemical Name:

    Benzenesulfonamide, 2-fluoro-5-methyl-4-(methyl((3S)-1-(phenylmethyl)-3-pyrrolidinyl)amino)-N-4-thiazolyl-

    SMILES Code: 

    O=S(C1=CC(C)=C(N(C)[C@@H]2CN(CC3=CC=CC=C3)CC2)C=C1F)(NC4=CSC=N4)=O

    InChi Code:

    InChI=1S/C22H25FN4O2S2/c1-16-10-21(31(28,29)25-22-14-30-15-24-22)19(23)11-20(16)26(2)18-8-9-27(13-18)12-17-6-4-3-5-7-17/h3-7,10-11,14-15,18,25H,8-9,12-13H2,1-2H3/t18-/m0/s1

    InChi Key:

    UCSHINHOAVARGQ-SFHVURJKSA-N

    Keyword:

    2154406-04-7;CAS:2154406-04-7;CAS:2154406-04-7;NBI-921352; NBI921352; NBI 921352; XEN901; XEN 901; XEN-901

    Solubility: To be determined

    Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

    Description: 

    NBI-921352 is a potent, highly selective Nav1.6 sodium channel inhibitor being developed to treat pediatric patients with SCN8A developmental and epileptic encephalopathy (SCN8A-DEE) and other potential indications, including adult focal epilepsy.

    Target: Efficient and highly selective Nav1.6 sodium channel inhibitor




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