Omaveloxolone; RTA 408

Chemical Name:

N-((4aR,6aR,6bS,12aS,14aR,14bR)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide

SMILES Code: 

CC(F)(F)C(N[C@]1(CCC(C)(C[C@@]1([C@]23[H])[H])C)CC[C@@]2(C)[C@]4(C)CCC5C(C)(C)C(C(C#N)=C[C@]5(C)C4=CC3=O)=O)=O

InChi Code:

InChI=1S/C33H44F2N2O3/c1-27(2)11-13-33(37-26(40)32(8,34)35)14-12-31(7)24(20(33)17-27)21(38)15-23-29(5)16-19(18-36)25(39)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3,(H,37,40)/t20-,22?,24+,29+,30-,31-,33-/m1/s1

InChi Key:

RJCWBNBKOKFWNY-HGNIWHNWSA-N

Keyword:

1474034-05-3；CAS：1474034-05-3；CAS:1474034-05-3；RTA408; RTA 408; RTA-408; Omaveloxolone

Solubility: Soluble in DMSO, not in water

Storage: Store at -20°C

Description: 

Omaveloxolone (RTA 408) is an antioxidant inflammatory modulator (AIM) that activates Nrf2 and inhibits nitric oxide (NO).

Target: Nrf2