OSI-027

Chemical Name:

(1r,4r)-4-(4-amino-5-(7-methoxy-1H-indol-2-yl)imidazo[5,1-f][1,2,4]triazin-7-yl)cyclohexane-1-carboxylic acid

SMILES Code: 

O=C(O)[C@H]1CC[C@@H](CC1)C2=NC(C3=CC4=C(C(OC)=CC=C4)N3)=C5C(N)=NC=NN52

InChi Code:

InChI=1S/C21H22N6O3/c1-30-15-4-2-3-13-9-14(25-16(13)15)17-18-19(22)23-10-24-27(18)20(26-17)11-5-7-12(8-6-11)21(28)29/h2-4,9-12,25H,5-8H2,1H3,(H,28,29)(H2,22,23,24)/t11-,12-

InChi Key:

JROFGZPOBKIAEW-HAQNSBGRSA-N

Keyword:

936890-98-1；CAS：936890-98-1；CAS:936890-98-1；OSI027；OSI-027；OSI 027

Solubility: Soluble in DMSO, not soluble in water

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years)

Description: 

OSI-027 (ASP7486) is an effective, selective, orally active, and ATP competitive mTOR kinase activity inhibitor.

Target: mTOR