Olinciguat; IW 1701

Chemical Name:

(R)-3,3,3-trifluoro-2-(((5-fluoro-2-(1-(2-fluorobenzyl)-5-(isoxazol-3-yl)-1H-pyrazol-3-yl)pyrimidin-4-yl)amino)methyl)-2-hydroxypropanamide

SMILES Code: 

O=C([C@](CNC1=NC(C2=NN(C(C3=NOC=C3)=C2)CC4=CC=CC=C4F)=NC=C1F)(C(F)(F)F)O)N

InChi Code:

InChI=1S/C21H16F5N7O3/c22-12-4-2-1-3-11(12)9-33-16(14-5-6-36-32-14)7-15(31-33)18-28-8-13(23)17(30-18)29-10-20(35,19(27)34)21(24,25)26/h1-8,35H,9-10H2,(H2,27,34)(H,28,29,30)/t20-/m1/s1

InChi Key:

YWQFJNWMWZMXRW-HXUWFJFHSA-N

Keyword:

1628732-62-6；CAS：1628732-62-6；CAS:1628732-62-6；Olinciguat, IW-1701, IW 1701, IW1701

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Olinciguat (IW-1701) is an orally administered guanylate cyclase (sGC) stimulant.

Target: guanylate cyclase, sGC