• Name: ND-630
  • Catalog No.: CPD1592
  • CAS No.: 1434635-54-7
  • Molecular Weight: 569.63
  • Chemical Formula: C28H31N3O8S
  • For scientific research only, not for patients.

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    Pack Size Availability Price (USD)
    10mg In stock 300
    50mg In stock 500
    100mg In stock 800
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    InChi Key:



    ND-630, ND630, ND 630, GS-0976, GS0976, GS 0976, NDI-010976, NDI010976, NDI 010976, Firsocostat, 1434635-54-7

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).


    ND-630 inhibits hACC1 (IC50=2.1±0.2 nM) and hACC2 (IC50=6.1±0.8 nM). Inhibition is reversible and highly specific for ACC. ND-630 inhibits ACC activity by interacting within the phosphopeptide-acceptor and dimerization site of the enzyme to prevent dimerization. ND-630 inhibits fatty acid synthesis with an EC50 of 66 nM in HepG2 cells without altering the total cell number, cellular protein concentration, and incorporation of acetate into cholesterol[1].

    Target: ACC

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