navlimetostatum; navlimetostat; MRTX 1719; BMS 986504

Chemical Name:

2-(4-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile

SMILES Code: 

O=C1C2=CC=C(C3=[C@]([C@]4=C(C#N)C(OC5CC5)=CC(Cl)=C4F)N(C)N=C3)C=C2C(CN)=NN1

InChi Code:

InChI=1S/C23H18ClFN6O2/c1-31-22(20-15(8-26)19(33-12-3-4-12)7-17(24)21(20)25)16(10-28-31)11-2-5-13-14(6-11)18(9-27)29-30-23(13)32/h2,5-7,10,12H,3-4,9,27H2,1H3,(H,30,32)

InChi Key:

BZKIOORWZAXIBA-UHFFFAOYSA-N

Keyword:

2630904-45-7；CAS：2630904-45-7；CAS:2630904-45-7；MRTX1719; MRTX 1719; MRTX-1719; BMS-986504; BMS986504; BMS 986504; navlimetostatum; navlimetostat

Solubility: 

Storage: Store at -20°C

Description: 

MRTX-1719 is an effective, orally active, and selective PRMT5 • MTA complex inhibitor.

Target: PRMT5•MTA