LRK 4189

Chemical Name:

(1S,4R)-4-(4-(4-(((S)-2,6-dioxopiperidin-3-yl)amino)-2-fluorophenyl)piperazin-1-yl)-N-((1r,4R)-4-((5-fluoro-4-(3-(2-oxopyridin-1(2H)-yl)phenyl)pyrimidin-2-yl)amino)cyclohexyl)cyclohexane-1-carboxamide

SMILES Code: 

FC1=CN=C(N[C@@H]2CC[C@@H](NC(=O)[C@@H]3CC[C@@H](N4CCN(C5=C(F)C=C(N[C@@H]6C(=O)NC(=O)CC6)C=C5)CC4)CC3)CC2)N=C1C1=CC(N2C(=O)C=CC=C2)=CC=C1

InChi Code:

InChI=1S/C43H49F2N9O4/c44-34-25-31(47-36-16-18-38(55)50-42(36)58)13-17-37(34)53-22-20-52(21-23-53)32-14-7-27(8-15-32)41(57)48-29-9-11-30(12-10-29)49-43-46-26-35(45)40(51-43)28-4-3-5-33(24-28)54-19-2-1-6-39(54)56/h1-6,13,17,19,24-27,29-30,32,36,47H,7-12,14-16,18,20-23H2,(H,48,57)(H,46,49,51)(H,50,55,58)/t27-,29-,30-,32-,36-/m0/s1

InChi Key:

JESQZBCEODMQQE-CKZBKQOKSA-N

Keyword:

3063346-83-5；CAS：3063346-83-5；CAS:3063346-83-5；LRK4189；LRK 4189；LRK-4189

Solubility: 

Storage: 

Description: 

LRK-4189 is an orally effective selective PIP4K2C degrader.

Target: PIP4K2C