GDC6036; GDC6036 atropisomers

Chemical Name:

2-Propen-1-one, 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-

SMILES Code: 

C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F)C3=NC(OC[C@H]5N(C)CCC5)=N2)CC1)=O

InChi Code:

InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32,33)34)15(2)11-20(35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6-10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1

InChi Key:

ZRBPIAWWRPFDPY-IRXDYDNUSA-N

Keyword:

2417917-17-8；CAS：2417917-17-8；CAS:2417917-17-8；GDC6036 atropisomers; GDC-6036; GDC 6036; GDC6036

Solubility: 

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

The GDC6036 anti rotation isomer contains two types of GDC6036 anti rotation isomers. GDC-6036， Also known as RG6330, it is an orally bioavailable, highly efficient, and selective KRAS G12C inhibitor.

Target: KRAS G12C