Crinecerfont; SSR125543

Chemical Name:

(S)-4-(2-chloro-4-methoxy-5-methylphenyl)-N-(2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl)-5-methyl-N-(prop-2-yn-1-yl)thiazol-2-amine

SMILES Code: 

C#CCN([C@H](C1=CC=C(C)C(F)=C1)CC2CC2)C3=NC(C4=CC(C)=C(OC)C=C4Cl)=C(C)S3

InChi Code:

InChI=1S/C27H28ClFN2OS/c1-6-11-31(24(13-19-8-9-19)20-10-7-16(2)23(29)14-20)27-30-26(18(4)33-27)21-12-17(3)25(32-5)15-22(21)28/h1,7,10,12,14-15,19,24H,8-9,11,13H2,2-5H3/t24-/m0/s1

InChi Key:

IEAKXXNRGSLYTQ-DEOSSOPVSA-N

Keyword:

752253-39-7；CAS：752253-39-7；CAS:752253-39-7；SSR125543；SSR-125543；SSR 125543；Crinecerfont

Solubility: Soluble in DMSO, not in water

Storage:  Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Crinecerfont (SSR-125543) is an effective, orally active, non peptide CRF1 receptor antagonist.

Target: CRF1 receptor