casdatifanum; casdatifan; AB521

Chemical Name:

(5R,6S,8R)-3,5,6-trifluoro-8-((1S,2R)-2-fluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)-5,6,7,8-tetrahydronaphthalene-1-carbonitrile

SMILES Code: 

FC(C=C1C#N)=CC2=C1[C@](C3=CC=C(S(=O)(C)=O)C4=C3C[C@](F)([H])[C@@]4([H])O)([H])C[C@]([H])(F)[C@@]2(F)[H]

InChi Code:

InChI=1S/C21H17F4NO3S/c1-30(28,29)17-3-2-11(13-7-16(24)21(27)19(13)17)12-6-15(23)20(25)14-5-10(22)4-9(8-26)18(12)14/h2-5,12,15-16,20-21,27H,6-7H2,1H3/t12-,15+,16-,20-,21-/m1/s1

InChi Key:

KHBHHNNBNHHGPE-QCCZFBHPSA-N

Keyword:

2709069-30-5；CAS：2709069-30-5；CAS:2709069-30-5；AB521；AB 521；AB-521；casdatifanum; casdatifan

Solubility: 

Storage: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Description: 

Casdaitifan (AB521) is an orally effective HIF-2 α (hypoxia inducible factor 2 α) inhibitor.

Target: HIF-2α