Tuspetinib; HM43239

Chemical Name:

rel-5-Chloro-N-[3-cyclopropyl-5-[[(3R,5S)-3,5-dimethyl-1-piperazinyl]methyl]phenyl]-4-(6-methyl-1H-indol-3-yl)-2-pyrimidinamine

SMILES Code: 

CC1=CC2=C(C=C1)C(C3=NC(NC4=CC(CN5C[C@@H](C)N[C@@H](C)C5)=CC(C6CC6)=C4)=NC=C3Cl)=CN2

InChi Code:

InChI=1S/C29H33ClN6/c1-17-4-7-24-25(12-31-27(24)8-17)28-26(30)13-32-29(35-28)34-23-10-20(9-22(11-23)21-5-6-21)16-36-14-18(2)33-19(3)15-36/h4,7-13,18-19,21,31,33H,5-6,14-16H2,1-3H3,(H,32,34,35)/t18-,19+

InChi Key:

FZLSDZZNPXXBBB-KDURUIRLSA-N

Keyword:

2294874-49-8；CAS：2294874-49-8；CAS:2294874-49-8；HM43239；HM-43239；HM 43239；Tuspetinib

Solubility: DMSO : 125 mg/mL (249.47 mM; Need ultrasonic)

Storage: 4°C, protect from light

Description: 

Tuspinib (HM43239) is a selective FLT3 inhibitor with oral activity.

Target: FLT3