BI-4924

Chemical Name:

2-{4-[(1S)-1-[(4,5-Dichloro-1,6-dimethyl-1H-indol-2-yl)formamido]-2-hydroxyethyl]benzenesulfonyl}acetic acid

SMILES Code: 

O=C(O)CS(=O)(C1=CC=C([C@H](NC(C(N2C)=CC3=C2C=C(C)C(Cl)=C3Cl)=O)CO)C=C1)=O

InChi Code:

InChI=1S/C21H20Cl2N2O6S/c1-11-7-16-14(20(23)19(11)22)8-17(25(16)2)21(29)24-15(9-26)12-3-5-13(6-4-12)32(30,31)10-18(27)28/h3-8,15,26H,9-10H2,1-2H3,(H,24,29)(H,27,28)/t15-/m1/s1

InChi Key:

CJEJFFCPVBZSIE-OAHLLOKOSA-N

Keyword:

2244452-09-1；CAS：2244452-09-1；CAS:2244452-09-1；BI-4924；BI 4924；BI4924

Solubility: Soluble in DMSO

Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months)

Description: 

BI-4924 is a lipophilic selective phosphoglycerate dehydrogenase (PHGDH) inhibitor that highly binds to plasma proteins.

Target: PHGDH