ARS-1620
Product Detail
Product Tags
| Pack Size | Availability | Price (USD) |
| 100mg | In Stock | 800 |
| 500mg | In Stock | 1500 |
| 1g | In Stock | 2000 |
| More Sizes | Get Quotes | Get Quotes |
Chemical Name:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
SMILES Code:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
InChi Code:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25-11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Keyword:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Solubility: Soluble in DMSO
Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months)
Description:
ARS-1620 is a prodrug designed from ARS-853, which is a potent and selective S-IIP G12C inhibitor. ARS-1620 is expected to be a therapeutic strategy for p.G12C KRAS mutant cancers.
Target: KRAS (K-Ras G12C)
