I-GSK2330672; i-linerixibat

Igama Lekhemikhali:

I-Pentanedioic acid, 3-(((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4- benzothiazepin-8-yl)methyl)amino)-

Ikhodi ye-SMILES:

O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2( =O)=O)CC(O)=O

Ikhodi ye-InChi:

I-InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15- 26(33)34)23(37-3)16-22(24)2 7(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27,29-30H,4-6,12,14-15,17-18H2, 1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1

I-InChi Key:

CZGVOBIGEBDYTP-VSGBNLITSA-N

Igama elingukhiye:

1345982-69-5;CAS:1345982-69-5;CAS:1345982-69-5;GSK-2330672; I-GSK 2330672; I-GSK2330672; i-linerixibat

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:Eyomile, emnyama futhi ku-0 - 4 C isikhathi esifushane (izinsuku ukuya emavikini) noma -20 C isikhathi eside (izinyanga kuya eminyakeni).

Incazelo:

I-Linerixibat (GSK2330672) iyisivimbeli esisebenza kahle kakhulu, esingamunceki, futhi esisebenzayo ngomlomo esiphezulu se-sodium esincike ku-bile acid (ASBT).

Ithagethi: ASBT