I-GSK2330672; linerixibat

Igama leMchiza:

Pentanedioic acid, 3-(((3R,5R)-3-butyl-3-ethyl-2,3,4,5-tetrahydro-7-methoxy-1,1-dioxido-5-phenyl-1,4- benzothiazepin-8-yl)methyl)amino)-

Ikhowudi yoncumo:

O=C(O)CC(NCC1=C(OC)C=C(C2=C1)[C@@H](C3=CC=CC=C3)N[C@](CC)(CCCC)CS2( =O)=O)CC(O)=O

Ikhowudi ye-InChi:

InChI=1S/C28H38N2O7S/c1-4-6-12-28(5-2)18-38(35,36)24-13-20(17-29-21(14-25(31)32)15- 26(33)34)23(37-3)16-22(24)27(30-28)19-10-8-7-9-11-19/h7-11,13,16,21,27, 29-30H,4-6,12,14-15,17-18H2,1-3H3,(H,31,32)(H,33,34)/t27-,28-/m1/s1

Isitshixo se-InChi:

CZGVOBIGEBDYTP-VSGBNLITSA-N

Igama elingundoqo:

1345982-69-5; CAS:1345982-69-5;CAS:1345982-69-5;GSK-2330672; GSK 2330672; I-GSK2330672; linerixibat

Ukunyibilika:Inyibilika kwi-DMSO

Ugcino:Yomile, emnyama kunye ne-0 - 4 C kwixesha elifutshane (iintsuku ukuya kwiiveki) okanye -20 C ixesha elide (iinyanga ukuya kwiminyaka).

Inkcazo:

I-Linerixibat (GSK2330672) yi-inhibitor esebenza kakuhle, engafunxanga, kwaye isebenzayo ngomlomo ephezulu exhomekeke kwi-sodium bile acid transporter (ASBT) inhibitor.

Ithagethi: ASBT