TYRA 300; dabogratinibum; dabogratinib

Chemical Name:

(R)-5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-3-(6-(6-(methylsulfonyl)-2,6-diazaspiro[3.3]heptan-2-yl)pyridin-3-yl)-1H-indazole

SMILES Code: 

O=S(N(C1)CC1(C2)CN2C(N=C3)=CC=C3C4=NNC5=CC=C(O[C@H](C)C6=C(Cl)C=NC=C6Cl)C=C54)(C)=O

InChi Code:

InChI=1S/C25H24Cl2N6O3S/c1-15(23-19(26)9-28-10-20(23)27)36-17-4-5-21-18(7-17)24(31-30-21)16-3-6-22(29-8-16)32-11-25(12-32)13-33(14-25)37(2,34)35/h3-10,15H,11-14H2,1-2H3,(H,30,31)/t15-/m1/s1

InChi Key:

JOAFWIHZEBKYQK-OAHLLOKOSA-N

Keyword:

2800223-30-5；CAS：2800223-30-5；CAS:2800223-30-5；TYRA-300；TYRA300；TYRA 300；dabogratinibum；dabogratinib

Solubility: 

Storage: 

Description: 

TYRA-300 is an orally effective FGFR3 selective inhibitor.

Target: FGFR3