Tolebrutinib

Chemical Name:

4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-(prop-2-enoyl)piperidin-3-yl]-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

SMILES Code: 

O=C(N1[C@H]2CN(C(C=C)=O)CCC2)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C1C=CN=C5N

InChi Code:

InChI=1S/C26H25N5O3/c1-2-23(32)29-16-6-7-19(17-29)30-22-14-15-28-25(27)24(22)31(26(30)33)18-10-12-21(13-11-18)34-20-8-4-3-5-9-20/h2-5,8-15,19H,1,6-7,16-17H2,(H2,27,28)/t19-/m1/s1

InChi Key:

KOEUOFPEZFUWRF-LJQANCHMSA-N

Keyword:

1971920-73-6；CAS:1971920-73-6；CAS：1971920-73-6；Tolebrutinib; SAR442168; SAR-442168; SAR 442168

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

Tolebrutinib, also known as SAR442168, is a Bruton tyrosine kinase inhibitor.

Target: Bruton's tyrosine kinase (Btk) inhibitor