STX-721
Product Detail
Product Tags
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Chemical Name:
(R,E)-3-((3-chloro-2-methoxyphenyl)amino)-2-(3-((1-(4-(dimethylamino)but-2-enoyl)-2-methylpyrrolidin-2-yl)ethynyl)pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one
SMILES Code:
O=C1NCCC2NC(=C(NC3C(OC)=C(Cl)C=CC=3)C1=2)C1C=CN=CC=1C#C[C@]1(CCCN1C(=O)/C=C/CN(C)C)C
InChi Code:
InChI=1S/C32H35ClN6O3/c1-32(14-7-19-39(32)26(40)10-6-18-38(2)3)15-11-21-20-34-16-12-22(21)28-29(27-24(36-28)13-17-35-31(27)41)37-25-9-5-8-23(33)30(25)42-4/h5-6,8-10,12,16,20,36-37H,7,13-14,17-19H2,1-4H3,(H,35,41)/b10-6+/t32-/m1/s1
InChi Key:
UMSJPISUMQOUKS-LMZGTLAXSA-N
Keyword:
2765525-82-2；CAS：2765525-82-2；CAS:2765525-82-2；STX721；STX 721；STX-721
Solubility:
Storage:
Description:
STX-721 is a mutation selective inhibitor of EGFR and HER2 exon 20 insertion (ex20ins) mutants.
Target: EGFR and HER2
