sovilnesib; sovilnesibum; AMG 650

Chemical Name:

2-(6-azaspiro[2.5]octan-6-yl)-N-[2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl]-4-(2- hydroxyethane-1-sulfonamido)benzamide

SMILES Code: 

O=C(NC1=NC(N2CCC(F)(F)CC2)=NC(C)=C1)C3=CC=C(NS(=O)(CCO)=O)C=C3N(CC4)CCC54CC5

InChi Code:

InChI=1S/C26H34F2N6O4S/c1-18-16-22(31-24(29-18)34-12-8-26(27,28)9-13-34)30-23(36)20-3-2-19(32-39(37,38)15-14-35)17-21(20)33-10-6-25(4-5-25)7-11-33/h2-3,16-17,32,35H,4-15H2,1H3,(H,29,30,31,36)

InChi Key:

KBDGEJDIHZDPHN-UHFFFAOYSA-N

Keyword:

2410796-79-9；CAS：2410796-79-9；CAS:2410796-79-9；sovilnesibum; sovilnesib; AMG650; AM 650; AMG-650

Solubility: 

Storage: Store at -20°C

Description: 

Sovilnesib (AMG 650) is an orally effective Kinesin like protein KIF18A inhibitor.

Target: kinesin-like protein KIF18A