NCATS-SM1441

Chemical Name:

2-(5-(cyclopropylmethyl)-4-(3-fluoro-4-sulfamoylbenzyl)-3-(3-((5-methylthiophen-2-yl)ethynyl)phenyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid

SMILES Code: 

CC1=CC=C(C#CC2=CC(C3=NN(C4=NC(C(O)=O)=CS4)C(CC5CC5)=C3CC6=CC=C(S(=O)(N)=O)C(F)=C6)=CC=C2)S1

InChi Code:

InChI=1S/C31H25FN4O4S3/c1-18-5-10-23(42-18)11-8-19-3-2-4-22(13-19)29-24(14-21-9-12-28(25(32)15-21)43(33,39)40)27(16-20-6-7-20)36(35-29)31-34-26(17-41-31)30(37)38/h2-5,9-10,12-13,15,17,20H,6-7,14,16H2,1H3,(H,37,38)(H2,33,39,40)

InChi Key:

LZIKVHXLVMNROK-UHFFFAOYSA-N

Keyword:

1964517-04-1；CAS：1964517-04-1；CAS:1964517-04-1；NCATS-SM1441；NCATS-SM-1441；NCATS-SM 1441

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

NCATS-SM1441 (compound 52) is a lactate dehydrogenase (LDH) inhibitor.

Target: LDH