MDK7526 HCl

MDK7526 HCl
  • Name: MDK7526 HCl; Protein degrader 1 hydrochloride
  • Catalog No.: CPDB1584
  • CAS No.: 1448189-80-7
  • Molecular Weight: 467.025
  • Chemical Formula: C22H31ClN4O3S
  • For scientific research only, not for patients.

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    Chemical Name:

    (2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

    SMILES Code: 


    InChi Code:


    InChi Key:



    MDK7526 HCl, Protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).


    MDK7526, also known as VHL Ligand 1; Protein degrader 1, is a potent and selective protein degrader. MDK7526 has CAS#1448297-52-6, its HCl salt has CAS#1448189-80-7. MDK7526 is potential useful for the targeted degradation of the androgen receptor. MDK7526 binds androgen receptor such that androgen receptor is placed in proximity to the ubiquitin ligase to effect degrdn. (and inhibition) of androgen receptor.

    Target: Androgen Receptor

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