GSK547

Chemical Name:

(S)-6-(4-(5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazole-1-carbonyl)piperidin-1-yl)pyrimidine-4-carbonitrile

SMILES Code: 

N#CC1=NC=NC(N2CCC(C(N3N=CC[C@H]3C4=CC(F)=CC(F)=C4)=O)CC2)=C1

InChi Code:

InChI=1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1

InChi Key:

SJVGFKBLUYAEOK-SFHVURJKSA-N

Keyword:

2226735-55-1；CAS：2226735-55-1；CAS:2226735-55-1；GSK547, GSK-547, GSK 547, RIP1i

Solubility: Soluble in DMSO

Storage: Store at -20°C

Description: 

GSK547 is a highly selective and potent inhibitor of RIP1 kinase that targets RIP1 in vivo

Target: RIP1