Enozertinib; ORIC-114

Chemical Name:

(R)-N-(4-((l6-oxidaneylidyne)methyl)-2-(4-(4-cyclopropylpiperazin-1-yl)piperidin-1-yl)-5-((6-(3-(3,5-difluorophenyl)isoxazolidin-2-yl)pyrimidin-4-yl)amino)phenyl)acrylamide

SMILES Code: 

FC1=CC(F)=CC([C@]2([H])N(C3=CC(NC4=C(C#[OH3])C=C(N5CCC(N6CCN(C7CC7)CC6)CC5)C(NC(C=C)=O)=C4)=NC=N3)OCC2)=C1

InChi Code:

InChI=1S/C35H42F2N8O3/c1-2-35(47)41-30-19-29(40-33-20-34(39-22-38-33)45-31(7-14-48-45)23-15-25(36)18-26(37)16-23)24(21-46)17-32(30)44-8-5-28(6-9-44)43-12-10-42(11-13-43)27-3-4-27/h2,15-20,22,27-28,31H,1,3-14H2,46H3,(H,41,47)(H,38,39,40)/t31-/m1/s1

InChi Key:

IVEDRGKAFFRYOT-WJOKGBTCSA-N

Keyword:

2489185-38-6；CAS：2489185-38-6；CAS:2489185-38-6；ORIC114；ORIC 114；ORIC-114；Enozertinib

Solubility: 

Storage: Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).

Description: 

Enozerinib is an EGFR inhibitor with anti-tumor activity.

Target: EGFR