CCT369260

Chemical Name:

5-((5-chloro-2-((3S,5R)-4,4-difluoro-3,5-dimethylpiperidin-1-yl)pyrimidin-4-yl)amino)-3-(3-hydroxy-3-methylbutyl)-1-methyl-1H-benzo[d]imidazol-2(3H)-one

SMILES Code: 

ClC1=C(NC2=CC(N(CCC(O)(C)C)C(N3C)=O)=C3C=C2)N=C(N4C[C@H](C)C(F)(F)[C@H](C)C4)N=C1

InChi Code:

InChI=1S/C24H31ClF2N6O2/c1-14-12-32(13-15(2)24(14,26)27)21-28-11-17(25)20(30-21)29-16-6-7-18-19(10-16)33(22(34)31(18)5)9-8-23(3,4)35/h6-7,10-11,14-15,35H,8-9,12-13H2,1-5H3,(H,28,29,30)/t14-,15+

InChi Key:

VFNPUAOAEFMXQI-GASCZTMLSA-N

Keyword:

2253878-44-1；CAS：2253878-44-1；CAS:2253878-44-1；5-((5-chloro-2-((3S,5R)-4,4-difluoro-3,5-dimethylpiperidin-1-yl)pyrimidin-4-yl)amino)-3-(3-hydroxy-3-methylbutyl)-1-methyl-1H-benzo[d]imidazol-2(3H)-one

Solubility: Soluble in DMSO

Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Description: 

CCT369260 is a potent BCL6 degrader.

Target: BCL6