BMS 986463

Chemical Name:

(S)-3-(5-(((S)-1-((8-fluoro-2-(tetrahydro-2H-pyran-4-yl)quinolin-6-yl)methyl)pyrrolidin-3-yl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

SMILES Code: 

O=C1C2C(=CC(O[C@@H]3CN(CC4=CC5=C(N=C(C=C5)C5CCOCC5)C(F)=C4)CC3)=CC=2)CN1[C@@H]1C(=O)NC(=O)CC1

InChi Code:

InChI=1S/C32H33FN4O5/c33-26-14-19(13-21-1-4-27(34-30(21)26)20-8-11-41-12-9-20)16-36-10-7-24(18-36)42-23-2-3-25-22(15-23)17-37(32(25)40)28-5-6-29(38)35-31(28)39/h1-4,13-15,20,24,28H,5-12,16-18H2,(H,35,38,39)/t24-,28-/m0/s1

InChi Key:

JPTNRZBZSUZXCS-CUBQBAPOSA-N

Keyword:

3025467-07-3；CAS：3025467-07-3；CAS:3025467-07-3；BMS986463；BMS 986463；BMS-986463

Solubility: 

Storage: 

Description: 

BMS-986463 is a CRBN E3 ligase modulator (CELMoD) and a WEE1 kinase molecular gel degrading agent.

Target: WEE1 kinase