BAY-1895344

BAY-1895344
  • Name: BAY-1895344
  • Catalog No.: CPDB1213
  • CAS No.: 1876467-74-1
  • Molecular Weight: 375.181
  • Chemical Formula: C20H21N7O
  • For scientific research only, not for patients.

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    Pack Size Availability Price (USD)
    50mg In Stock 400
    100mg In Stock 600
    1g In Stock 1750
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    Chemical Name:

    (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine

    SMILES Code: 

    CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=CC=NN5)N=CC=C24.[H]Cl

    InChi Code:

    InChI=1S/C20H21N7O.ClH/c1-13-12-28-10-9-27(13)18-11-15(17-5-8-23-26(17)2)14-3-6-21-20(19(14)24-18)16-4-7-22-25-16;/h3-8,11,13H,9-10,12H2,1-2H3,(H,22,25);1H/t13-;/m1./s1

    InChi Key:

    KWQNBYGUBHMRPY-BTQNPOSSSA-N

    Keyword:

    BAY-1895344, BAY1895344, BAY 1895344, 1876467-74-1

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    BAY-1895344 is a selective ATR (ataxia-telangiectasia and Rad3 related protein) inhibitor that inhibits proliferation of a broad spectrum of human tumor cell lines (median IC50 = 78 nM). BAY-1895344 is developed for the treatment of patients with advanced solid tumors and lymphomas, and it is undergoing a phase I clinical trial of safety and tolerability for cancer patients.

    Target: ATR


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