UJN49930; UGT8 Inhibitor 19; CGT Inhibitor 19; UGT8-IN-1

UJN49930; UGT8 Inhibitor 19; CGT Inhibitor 19; UGT8-IN-1
  • Name: 1-(3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl)piperidin-4-yl (S)-(1-(trifluoromethoxy)propan-2-yl)carbamate
  • Catalog No.: CPD106634
  • CAS No.: 2414349-93-0
  • Molecular Weight: 528.47
  • Chemical Formula: C20 H22 F6 N4 O4 S
  • For scientific research only, not for patients.

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    Chemical Name:

    1-(3-(methylcarbamoyl)-7-(trifluoromethyl)thieno[3,2-b]pyridin-5-yl)piperidin-4-yl (S)-(1-(trifluoromethoxy)propan-2-yl)carbamate

    SMILES Code: 

    CNC(C1=CSC2=C(C(F)(F)F)C=C(N3CCC(OC(N[C@H](COC(F)(F)F)C)=O)CC3)N=C12)=O

    InChi Code:

    InChI=1S/C20H22F6N4O4S/c1-10(8-33-20(24,25)26)28-18(32)34-11-3-5-30(6-4-11)14-7-13(19(21,22)23)16-15(29-14)12(9-35-16)17(31)27-2/h7,9-11H,3-6,8H2,1-2H3,(H,27,31)(H,28,32)/t10-/m0/s1

    InChi Key:

    UQQUABVWYAPTIQ-JTQLQIEISA-N

    Keyword:

    2414349-93-0;CAS:2414349-93-0;CAS:2414349-93-0;UJN49930; UJN 49930; UJN-49930; UGT8 Inhibitor 19; Ceramide Galactosyltransferase Inhibitor 19; CGT Inhibitor 19; UDP-galactose Ceramide Galactosyltransferase Inhibitor 19

    Solubility: DMF:30.0(Max Conc. mg/mL);56.77(Max Conc. mM) DMSO:30.0(Max Conc. mg/mL);56.77(Max Conc. mM) Ethanol:25.0(Max Conc. mg/mL);47.31(Max Conc. mM)

    Storage: 

    Description: 

    UGT8-IN-1 is an orally active inhibitor of ceramide galactosyltransferase (UGT8) that can cross the blood-brain barrier.

    Target: UGT8




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