NST-628

Chemical Name:

3--[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

SMILES Kodhi:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

InChi Code:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26 , 28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Keyword:

3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628;

Solubility: 

Kuchengeta:Yakaoma, yakasviba uye pa 0 -4 C kwenguva pfupi (mazuva kusvika kumavhiki) kana -20 C kwenguva refu (mwedzi kusvika kumakore).

Tsanangudzo:

NST-628 iMAPK nzira yemamorekuru gel ine ropa-brain barriers permeability, iyo inogona kutadzisa RAF phosphorylation uye MEK activation.

Chinangwa: RAF phosphorylation uye MEK