Tavapadon

Ingoa matū:

1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione

Waehere SMILES:

O=C1NC(C(C)=C(C2=CC=C(OC3=NC=CC=C3C(F)(F)F)C=C2C)N1C)=O

Waehere InChi:

InChI=1S/C19H16F3N3O3/c1-10-9-12(28-17-14(19(20,21)22)5-4-8-23-17 )6-7-13(10)15-11(2)16(26)24-18(27)25(15)3/h4-9H,1-3H3,(H,24,26,27)

Kī InChi:

AKQXQLUNFKDZBN-UHFFFAOYSA-N

Kupumatua:

1643489-24-0；CAS:1643489-24-0；CAS：1643489-24-0；Tavapadon; PF-6649751; PF 6649751; PF6649751; CVL-751; CVL 751; CVL751

Wairewa:Wairewa i roto i te DMSO

Rokiroki:He maroke, he pouri me te 0 - 4 C mo te wa poto (ra ki nga wiki) ranei -20 C mo te wa roa (marama ki nga tau).

Whakaahuatanga:

Ko Tavapadon, e mohiotia ana ko PF-6649751 me CVL-751, he agonist kaikawe dopamine waahanga. Ka whai hua pea mo te maimoatanga o te mate Parkinson me te Alzheimer's.

Whainga: Dopamine d1/d5 kaiawhina agonists waahanga