VU0448088 (ML253)

Gemyske namme:

3-amino-5-chlor-4,6-dimethyl-N-(pyridin-4-ylmethyl)thieno[2,3-b]pyridine-2-carboxamide

SMILES Koade:

CC1=NC2=C(C(N)=C(S2)C(NCC3=CC=NC=C3)=O)C(C)=C1Cl

InChi Koade:

InChI=1S/C16H15ClN4OS/c1-8-11-13(18)14(23-16(11)21-9(2)12(8)17)15(22)20-7-10-3-5- 19-6-4-10/h3-6H,7,18H2,1-2H3,(H,20,22)

InChi Key:

XNCQMFVABACABG-UHFFFAOYSA-N

Keyword:

1417616-42-2; CAS: 1417616-42-2; CAS: 1417616-42-2; VU0448088; ML253; ML 253; ML-253

Oplosberens: 

Opslach: 

Beskriuwing:

VU0448088 (ML253) is in effektive positive allosteryske modulator fan tricyclyske muscarinyske acetylcholine-receptor subtype 4 (M4) dy't de bloed-harsensbarriêre kin oerstekke.

Doel: tricyclyske muskarine acetylcholine receptor subtype 4 (M4)