| KASS nr | Toote nimi | Kirjeldus |
| CPDB3713 | DEL-22379 | DEL-22379 on tugev ja selektiivne ERK dimerisatsiooni inhibiitor. DEL-22379 inhibeerib ERK dimerisatsiooni, mõjutamata ERK fosforüülimist, hoiab ära RAS-ERK raja onkogeenide poolt juhitud tuumorigeneesi. Peaaegu 50% inimese pahaloomulistest kasvajatest on reguleerimata RAS-ERK signaaliülekandega; selle inhibeerimine on sobiv strateegia kasvajavastaseks sekkumiseks. |
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