TH-302; Evofosfamide

TH-302; Evofosfamide
  • Name: TH-302; Evofosfamide
  • Catalog No.: CPDB1510
  • CAS No.: 918633-87-1
  • Molecular Weight: 449.04
  • Chemical Formula: C9H16Br2N5O4P
  • For scientific research only, not for patients.

    Product Detail

    Product Tags

    Pack Size Availability Price (USD)
    100mg In Stock 360
    1g In Stock 1000
    More Sizes Get Quotes Get Quotes

    Chemical Name:

    N,N'-Bis(2-bromoethyl)phosphorodiamidic acid (1-methyl-2-nitro-1H-imidazol-5-yl)methyl ester

    SMILES Code: 


    InChi Code:


    InChi Key:



    TH-302, TH302, TH 302, Evofosfamide, 918633-87-1

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months)


    Evofosfamide, also known as TH-302, is a hypoxia-activated prodrug consisting of a 2-nitroimidazole phosphoramidate conjugate with potential antineoplastic activity. The 2-nitroimidazole moiety of hypoxia-activated prodrug TH-302 acts as a hypoxic trigger, releasing the DNA-alkylating dibromo isophosphoramide mustard moiety within hypoxic regions of tumors. Normoxic tissues may be spared due to the hypoxia-specific activity of this agent, potentially reducing systemic toxicity. Check for active clinical trials or closed clinical trials using this agent. (NCI).

    Target: DNA Alkylating Agent

  • Previous:
  • Next:

  • Related Products

    WhatsApp Online Chat !