Vactosertib; TEW 7197

Chemical Name:

N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline

SMILES Code: 

FC1=CC=CC=C1NCC2=NC(C3=CN4C(C=C3)=NC=N4)=C(C5=NC(C)=CC=C5)N2

InChi Code:

InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)

InChi Key:

FJCDSQATIJKQKA-UHFFFAOYSA-N

Keyword:

1352608-82-2；CAS：1352608-82-2；CAS:1352608-82-2；TEW7197; TEW 7197; TEW-7197; Vactosertib

Solubility: Soluble in DMSO, not in water

Storage: Refrigerator

Description: 

Vactosertib (EW-7197) is an effective, orally active, and ATP competitive activator receptor like kinase 5 (ALK5) inhibitor.

Target: ALK5