Ertugliflozin

Ertugliflozin
  • Name: Ertugliflozin
  • Catalog No.: CPDA0004
  • CAS No.: 1210344-57-2
  • Molecular Weight: 436.88
  • Chemical Formula: C22H25ClO7
  • For scientific research only, not for patients.

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    Chemical Name:

    (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol

    SMILES Code: 

    "CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C34C(C(C(C(O3)(CO4)CO)O)O)O)Cl "

    InChi Code:

    "InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22-/m0/s1 "

    InChi Key:

    "MCIACXAZCBVDEE-CUUWFGFTSA-N "

    Keyword:

    Ertugliflozin, PF 04971729,MK-8835,1210344-57-2

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    Ertugliflozin, also known as also known as PF-04971729, is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 and clinical candidate for the treatment of type 2 diabetes mellitus. clinical study showed that Ertugliflozin (1-25 mg/day) improved glycaemic control, body weight and blood pressure in patients with T2DM suboptimally controlled on metformin, and was well tolerated.

    Target: SGLT-2


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