Resmetirom

Resmetirom
  • Name: Resmetirom
  • Catalog No.: CPD2046
  • CAS No.: 920509-32-6
  • Molecular Weight: 435.22
  • Chemical Formula: C17H12Cl2N6O4
  • For scientific research only, not for patients.

    Product Detail

    Product Tags

    Pack Size Availability Price (USD)

    Chemical Name:

    Resmetirom

    SMILES Code: 

    N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O

    InChi Code:

    InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28)

    InChi Key:

    FDBYIYFVSAHJLY-UHFFFAOYSA-N

    Keyword:

    MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom

    Solubility: Soluble in DMSO, not in water

    Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months)

    Description: 

    Resmetirom, also known as MGL-3196, is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor β (THR-β) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor α (THR-α).

    Target: THR-β


  • Previous:
  • Next:

  • Related Products

    
    WhatsApp Online Chat !