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MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom
Solubility: Soluble in DMSO, not in water
Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months)
Resmetirom, also known as MGL-3196, is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia. The beneficial effects of thyroid hormone (TH) on lipid levels are primarily due to its action at the thyroid hormone receptor β (THR-β) in the liver, while adverse effects, including cardiac effects, are mediated by thyroid hormone receptor α (THR-α).