MB-07811

MB-07811
  • Name: MB-07811
  • Catalog No.: CPD2053
  • CAS No.: 852948-13-1
  • Molecular Weight: C28H32ClO5P
  • Chemical Formula: 514.98
  • For scientific research only, not for patients.

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    Chemical Name:

    (2R,4S)-4-(3-chlorophenyl)-2-((4-(4-hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)methyl)-1,3,2-dioxaphosphinane 2-oxide

    SMILES Code: 

    OC1=CC=C(CC2=C(C)C=C(OC[P@]3(OCC[C@@H](C4=CC=CC(Cl)=C4)O3)=O)C=C2C)C=C1C(C)C

    InChi Code:

    InChI=1S/C28H32ClO5P/c1-18(2)25-14-21(8-9-27(25)30)15-26-19(3)12-24(13-20(26)4)32-17-35(31)33-11-10-28(34-35)22-6-5-7-23(29)16-22/h5-9,12-14,16,18,28,30H,10-11,15,17H2,1-4H3/t28-,35+/m0/s1

    InChi Key:

    LGGPZDRLTDGYSQ-JADSYQMUSA-N

    Keyword:

    MB 07811; MB07811; MB-07811; MB-07344; MB 07344; MB07344

    Solubility: 

    Storage: 

    Description: 

    "MB-07811, also known as MB-07344, is a thyroid hormone receptor beta (TRB) agonist potentially for the treatment of hyperlipidemia. The prodrug [MB07811] of a novel phosphonate-containing thyroid hormone receptor agonist [MB07344] is the first application of the HepDirect liver-targeting approach to a non-nucleotide agent. "

    Target: THR-β


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