BAZ2-ICR

BAZ2-ICR
  • Name: BAZ2-ICR
  • Catalog No.: CPDB1614
  • CAS No.: 1665195-94-7
  • Molecular Weight: 357.41
  • Chemical Formula: C20H19N7
  • For scientific research only, not for patients.

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    100mg In Stock 500
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    Chemical Name:

    4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile

    SMILES Code: 

    CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2

    InChi Code:

    InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3

    InChi Key:

    RRZVGDGTWNQAPW-UHFFFAOYSA-N

    Keyword:

    BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7

    Solubility: Soluble in DMSO

    Storage: 0 - 4°C for short term (days to weeks), or -20°C for long term (months).

    Description: 

    BAZ2-ICR is an excellent chemical probe for functional studies of the BAZ2 bromodomains in vitro and in vivo. The bromodomain containing proteins BAZ2A/B play essential roles in chromatin remodeling and regulation of noncoding RNAs. BAZ2-ICR has IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; solubility 25 mM (D2O) and F = 70%.

    Target: BAZ2


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